"It's a cool thing," Weaver said Saturday. "Obviously, I was able to do it [in 2008 and 2010]. I don't take it as being more special than being one of five [starters]. I don't build it up too much."
The righty this spring pitched 17 2/3 innings, tallying two wins, striking out 21 and walking only two.
In his two previous Opening Day starts, Weaver lost, 3-2, in 2008 at Minnesota and then beat the Twins, 6-3, last year.
"Jered has been here awhile and is the leader of the staff," right-hander Dan Haren said. "He has been an Angel from the beginning. He is the one we will turn to."
After Weaver, the rotation is set to be Haren, Ervin Santana and then Scott Kazmir.
With an off-day Wednesday and two at the beginning of April, the Angels can go with a four-man rotation until Joel Pineiro, who will begin the season on the disabled list, can return for the home opener April 8 against the Toronto Blue Jays.
"With the off-days, we will stay at a four-man rotation until Joel folds in," said Scioscia.
Even with Pineiro on the DL for the beginning of the season with muscle soreness in his back, Haren believes that the starting rotation can be dominant.
"We have a good staff and I am excited to get it going," Haren said. "It will be fun to watch Jered out there."