One of the game's most promising young sluggers since 2005, Wood was designated for assignment on Tuesday night to make room on the 25-man roster for shortstop Erick Aybar, who has been on the disabled list with a strained left oblique.
The move gives the club seven days to place the player on waivers and 10 days to waive, trade or release him. If no trade can be completed, Wood, 26, likely would be claimed if placed on waivers, manager Mike Scioscia said.
A shortstop when he was taken in the first round of the 2003 First-Year Player Draft out of Horizon High School in Scottsdale, Ariz., Wood put up huge numbers throughout the Minor Leagues. But he fell flat in 2010 when he claimed third base out of Spring Training with the departure of Chone Figgins.
Wood batted .146 in 81 games with four homers and 14 RBIs, but it did not negatively impact his defense, which was first rate.
Playing shortstop primarily in six games this year -- the team was 4-0 when he started there -- Wood was hitting .143 in 14 at-bats with a double.
"The last two games, I've felt like myself," Wood said. "I played baseball. I didn't care about numbers. How I felt at shortstop and in the batter's box was me.
"I got the opportunity to lock it down last year and it didn't happen. These guys can play. I didn't do it last year, but getting a chance to prove myself and redeem myself is something I want.
"This just happened, so I'm a little numb to everything now. There are tears and thoughts about all the people who I've been so close to. This is the organization I've loved since I was 18 years old, going through the Minor Leagues. It's tough."
Solid defensively at three positions, including first base, Wood produced 161 home runs and 542 RBIs in 764 Minor League games, starting in rookie ball in 2003. He's a .284 career hitter in the Minors.
"This is tough -- he's one of our guys," said Scioscia, who has an abundance of infielders with Aybar returning to join Maicer Izturis, Howard Kendrick and Alberto Callaspo. "We all had high expectations for what he was going to do. His struggle was well documented last year.
"Baseball wasn't fun for Brandon last year or this year. He's a great kid. We don't have the development at the Major League level he needs. He needs to go out and play and have baseball be fun again.
"His expectations were higher than ours. That could have been part of the dilemma."
There was "just no roster flexibility," Scioscia said. "Brandon needs to go play and establish his career. We'll be proud of what happens. Most likely there will be a place for Woody in the big leagues ... I'm sure."
Lyle Spencer is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.