"I feel good," Colon said through an interpreter. "If anything, my arm is a little tight and it didn't allow me to get loose, but I don't want to use that as an excuse for me not locating pitches and them killing me for it."
Colon said the tightness started when he was finishing up in the bullpen before the game and added that he did not think it would affect his next start.
"Bart wasn't at his best tonight," said Scioscia. "He left some balls up in the zone late, and it hurt him. We'll have to review the outing and see what went wrong."
Fresh off a three-game sweep of the Yankees in New York, the Angels couldn't piece together the necessary elements to stop Seattle's offense.
The Mariners have now scored 38 runs over their past four games, and they scored early and often Monday night.
Down by two going in to the third inning, the Angels kept pace by adding one run in both the third and fourth to tie the score at 4, but a two-run sixth and a six-run seventh for the Mariners did the Angels in.
After Jose Guillen's sacrifice fly in the seventh chased Colon and made the score 7-4, Hector Carrasco entered the game and allowed a three-run shot to Richie Sexson. Two batters later, Adrian Beltre launched his second homer of the game deep into the bleachers in left field.
Seattle center fielder Ichiro Suzuki extended his hitting streak to 21-games with a single in the seventh inning.
"We got behind, and it was tough to get going," Scioscia said. "We probably gave them five or six extra outs, and when they're swinging the bats as hot as they have been the past couple of weeks, you just can't do that."
Scioscia missed the last two games of the weekend series in New York to attend graduation ceremonies for his son, Matt, in Los Angeles.
Angels bench coach Ron Roenicke filled in for Scioscia during his absence and earned two victories. Roenicke has a record of 5-0 over the past two seasons when subbing for Scioscia.
Angels catcher Mike Napoli extended his hitting streak to a career-best 14 games with a single to left in the bottom of the eighth inning.
Casey Kotchman's streak of 115 games without an error ended in the seventh inning when he threw wide to second trying to start a double play off of Raul Ibanez's grounder. Suzuki scored the Mariners' eighth run on the play.
Angels outfielder Nathan Haynes, called up earlier in the day from Triple-A Salt Lake, made his Major League debut with a pinch-hit single in the ninth for his first Major League hit. He scored later in the inning on Kendry Morales' fielder's choice.
"My heart was racing," Haynes said. "But I was anxious as opposed to scared."
The Angels loss snapped a five-game home winning streak, and Scioscia was ready to forget about it right after the game ended.
"A loss is a loss," said the manager. "We didn't pitch the way we can, but it's a loss. You turn the page and hopefully come out better tomorrow night."