Oakland makes an early appearance for a four-game AL West series in Anaheim starting April 16. Seattle's first Angel Stadium visit comes from June 4-6.
Interleague Play in 2012 for manager Mike Scioscia's troupe will feature National League West teams. The Angels initiate the action in San Diego against manager Bud Black's Padres in a three-game series starting on May 18.
Following that series, the Angels hit the road for AL West destinations Oakland and Seattle. Improving their play inside the division will be a major focus for Scioscia and Co. after experiencing difficulties with the A's, especially, and also the Rangers this season.
The Yankees pay their lone visit to Angel Stadium for a three-game series opening on May 28. That will be followed by three games against Texas, the Rangers' first trip to Anaheim.
A six-game trip will pick up Interleague Play on June 8 with a three-game series at Coors Field in Denver against the Rockies. The Angels then will get their first look at their traditional rivals, the Dodgers, at Dodger Stadium starting on June 11.
The D-backs will visit Angel Stadium on June 15 for three games, followed by the Giants for a three-game set. The Angels conclude Interleague Play with the Dodgers at Angel Stadium in a three-game set June 22-24.
The Angels have a history of flourishing in Interleague Play with a 152-124 record. They were 13-5 this season while facing the NL East and the Dodgers.
The longest homestand of the season will be a 10-game stretch from Aug. 10-19, bringing Seattle, Cleveland and Tampa Bay to Southern California. It will be a four-game series with the Rays, who also come to Anaheim in July.
The Angels will have home-and-home series against Boston in August. In a challenging trip, the Halos visit Fenway Park for three games starting Aug. 21 followed by three games against the Tigers at Comerica Park.
Returning home, they'll face Boston three more times starting on Aug. 28.
In contrast to this season, with a final road trip taking them to Baltimore and Toronto in the Eastern Time Zone, the Angels will travel only once outside the AL West next September, for a three-game series with the AL Central's Royals from Sept. 14-16. Series against the Tigers (Sept. 7-9) and the White Sox (Sept. 21-23) will be staged at Angel Stadium.