Wilson, who signed with the Angels this offseason, worked four innings and allowed a run on three hits in his third start of the spring. He worked out of trouble in the second and third, but allowed a run to score when Reds right fielder Dennis Phipps ripped his second double of the day in the top of the fourth.
For the Reds, starter Johnny Cueto looked a bit shaky early, but he settled down to allow two runs (one earned) in four innings. Cueto allowed four hits in the first two frames, but held the Angels hitless in the last two, with a pair of strikeouts in the fourth.
Erick Aybar scored the Angels' first run after he opened the first inning by lacing a triple down the right-field line. He scored two outs later on Torii Hunter's single. The Halos tacked on another in the second when Hank Conger singled home an unearned run.
Both Hunter and Conger were picked off at first base to end the first and second innings, respectively, after a very sharp, quick pick-off move by Cueto caught them leaning toward second base.
A day after Angels slugger Albert Pujols blasted his first two home runs of the season, he went 0-for-3.
Up next: The Angels are set for split-squad action on Friday, with a game at home against Cleveland at 1:05 p.m. PT and a road trip to face San Diego at the same time on the schedule. Garrett Richards gets the ball for the side staying in Tempe, while Brad Mills squares off against Tim Stauffer in Peoria. Veteran reliever Jason Isringhausen will make his spring debut for the team after he signed at the end of February.
AJ Cassavell is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.