Hunter sat on a 2-1 pitch from Rays starter Edwin Jackson and knocked it over the left-center-field wall to give the Angels a 4-3 lead in the bottom of the fourth inning. Vladimir Guerrero, who singled to lead off the inning, scored on Hunter's blast.
It was the eighth home run of the year for Hunter, who signed a five-year, $90 million free agent contract this past offseason to play center field for the Angels.
Hunter's impact on the American League West-leading Angels has been felt on both sides of the ball. He has not committed an error while providing solid defense in center, and also leads the team with 34 runs scored and 106 total bases.
The 32-year-old drilled a walk-off grand slam at home on April 7 against the Indians, and tied a club record with three doubles in a single game on April 18 against Seattle. Hunter's first homer as an Angel came April 3 at Minnesota, his big league home for the previous 10 seasons.
Mike Scarr is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.