Pujols was pulled from Wednesday's 7-3 win over the Sox in the bottom of the fourth inning after experiencing some tightness in his calf while running the bases. Thursday was the first game this year the first baseman did not start due to injury.
"I feel a little bit better," Pujols said before Thursday's game. "I'm actually walking better. Hopefully it's nothing too bad. Just day to day hopefully."
How long will Pujols be sidelined?
"I really don't know. I think the fact that he's up and walking [is good]," Angels manager Mike Scioscia said. "If that was the seventh game of the World Series yesterday, he's staying in that game. Hopefully we will get some good news, but we have to wait for these guys to evaluate it."
Mark Trumbo made his eighth start at first base on Thursday. With Trumbo moving from left field to the infield, the Angels have just three outfielders and 11 healthy position players. The club is not considering a roster move yet, though.
"I think right now, we're going to wait to see where we are," Scioscia said. "One thing is we're a little limited on the offensive side right now. But considering where our pitching staff is and trying to get it moving in the right direction I think the extra arm could help."
Pujols is hitting .283 with 28 home runs and 86 RBIs. He leads the team with 121 games played. The slugger leads the Major Leagues with 14 homers since the All-Star break.