"He's very sore," Scioscia said. "Most likely DL."
Thatcher was walking around the locker room on crutches after the game, with his ankle wrapped. He said the ankle wasn't broken, but that he would likely be out a few weeks and is targeting a return before the end of August.
Thatcher pulled up hobbling trying to chase down Brandon Guyer's bunt single down the third-base line. It was the left-hander's first time pitching since July 21.
The Angels' trainers met the limping Thatcher out by third base to examine him, and eventually helped Thatcher off the field.
Thatcher had entered the game to start the fourth with the Angels trailing, 6-3, and threw 15 pitches before exiting. He was replaced by Michael Roth.
David Adler is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.